New Treatment Option for Alzheimer's Disease

On the reasoning that oxidative stress is a hallmark of Alzheimer's Disease, researchers at the Department of Rehabilitation and Geriatrics in Hannover, Germany hypothesized that an antioxidant supplement, alpha-lipoic acid, might slow the progression of the disease.

As reported in the 2007 issue of the Journal of Neural Transmission (number 72), 43 patients with Alzheimer's Disease were given 600 mg of alpha-lipoic acid per day over an observation period of 4 years. Using standardized measures of functioning for Alzheimer's patients, the authors concluded that alpha-lipoic acid markedly slowed the progression of the disease compared to patients receiving no treatment as well as to patients receiving choline-esterase inhibitors.

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